This study investigates the manufacture of mPEG-PLA diblock copolymers through a controlled ring-opening polymerization. Various reaction conditions, including monomer concentration, were optimized to achieve desired molecular weights and polydispersity indices. The resulting copolymers were analyzed using techniques such as size exclusion chromato… Read More

Poly(lactic acid) polylactic acid (PLA) is a versatile biocompatible polymer widely used in drug delivery systems. However, its rapid degradation and poor water solubility limit its efficacy. To overcome these challenges, PEGylation, the process of attaching polyethylene glycol PEG, has emerged as a promising strategy. Biocompatible PEGylation enha… Read More